Publications...

Schenk N*, Dahl PJ*, Hanna M, Audhya A, Tall GG, Knight JD, Anantharam A. A simple supported tubulated bilayer system for evaluating protein-mediated membrane remodeling. Chemistry and Physics of Lipids. 2018; Sep; 215: 18-28.

Gil de Rubio R, Malik S, Yule DI, Anantharam A, Smrcka AV. Phosphatidylinositol 4-Phosphate is a Major Substrate for GPCR-stimulated Phosphoinositide Hydrolysis. Science Signaling. 2018; Sep 11; 11 (547).

MacDougall DD, Lin Z, Chon NL, Jackman SL, Lin H, Knight JD, Anantharam A. Synaptotagmin-7 is a high affinity calcium- sensor that serves multiple roles in regulated exocytosis. J Gen Physiol. 2018; Jun 4; 150(6):783-807.

Bendahmane M, Bohannon KP, Rao TC, Schmidtke MW, Bradberry MM, Abbineni P, Chon N, Tran S, Lin H, Chapman ER, Knight JD, Anantharam A. The synaptotagmin C2B domain calcium-binding loops modulate the rate of fusion pore expansion. Molecular Biology of the Cell. 2018; Apr 1; 29(7): 834-845.

Rao TC, Santana Rodriguez Z, Bradberry MM, Ranski AH, Dahl PJ, Schmidtke MW, Jenkins PM, Axelrod D, Chapman ER, Giovannucci DR, Anantharam A. Synaptotagmin isoforms confer distinct activation kinetics and dynamics to chromaffin cell granules. J Gen Physiol 2017; Aug 7; 149(8):763-780.

Holz RW, Anantharam A. Food deprivation induces presynaptic plasticity in the autonomic nervous system. PNAS 2016; 113 (21): 5766-5767.

Rao TC, Passmore DR, Peleman AR, Das M, Chapman ER, Anantharam A. Distinct fusion properties of synaptotagmin-1 and synaptotagmin-7 bearing dense core granules. Molecular Biology of the Cell. 2014; 25(16):2416-27.

Weiss AN, Anantharam A, Bittner MA, Axelrod D, Holz RW. Lumenal Protein within Secretory Granules Affects Fusion Pore Expansion. Biophysical Journal. 2014; 107(1):26-33.

Passmore DR, Rao TC, Peleman AR, Anantharam A. Imaging plasma membrane deformations with pTIRFM. Journal of Visualized Experiments: JoVE 2014(86).

Passmore DR, Rao T, Anantharam A. Real time investigation of plasma membrane deformation and fusion pore expansion using polarized TIRFM.  Methods in Molecular Biology 2014; 1174: 263-73.

Anantharam A, Axelrod D, Holz RW. Real-time imaging of plasma membrane deformations reveals pre-fusion membrane curvature changes and a role for dynamin in fusion pore expansion.  Journal of Neurochemisty 2012; 122(4): 661-671.

Lama RD, Charlson K, Anantharam A, Hashemi P. Ultra-fast detection and quantification of brain signaling molecules with carbon fiber microelectrodes.  Analytical Chemistry 2012; 84(19): 8096-101.

Jenkins PM, McIntyre JC, Zhang L, Anantharam A, Vesely ED, Arendt KL, Carruthers CJ, Kerppola TK, Iñiguez-Lluhí JA, Holz RW, Sutton MA, Martens JR. Subunit-dependent axonal trafficking of distinct alpha heteromeric potassium channel complexes. Journal of Neuroscience 2011; 31(37): 13224-13235.

Anantharam A, Bittner MA, Aikman RL, Stuenkel EL, Schmid SL, Axelrod D, Holz RW. A new role for the dynamin GTPase in the regulation of fusion pore expansion. Molecular Biology of the Cell 2011; 22(11): 1907-1918.

Anantharam A, Onoa B, Edwards RH, Holz RW, Axelrod D. Localized topological changes of the plasma membrane upon exocytosis visualized by polarized TIRFM. Journal of Cell Biology 2010; 188(3): 415-428.

Anantharam A, Axelrod D, Holz RW. Polarized TIRFM reveals changes in plasma membrane topology before and during granule fusion. Cellular and Molecular Neurobiology 2010; 30(8): 1343-1349, 2010.

Anantharam A, Palmer LG. Determination of epithelial Na+ channel subunit stoichiometry from single-channel conductances. J Gen Physiol. 2007; 130(1): 55-70, 2007.

Roepke TK, Anantharam A, Kirchhoff P, Busque SM, Young JB, Geibel JP, Lerner DJ, Abbott GW. The KCNE2 potassium channel ancillary subunit is essential for gastric acid secretion. J Biol Chem 2006; 281(33): 23740-23747.

Anantharam A, Tian Y, Palmer LG. Open probability of the epithelial sodium channel is regulated by intracellular sodium. J Physiol (Lond.) 2006; 574(2): 333-347.

Anantharam A, Abbott GW. Does hERG coassemble with a ß subunit? Evidence for roles of MinK and MiRP1. Novartis Foundation Symposium. 2005; 100-112, 2005.

Anantharam A, Markowitz SM, Abbott GW. Pharmacogenetic Considerations in Diseases of Cardiac Ion Channels. J Pharmacol Exp Ther 2003; 307(3): 831-838.

Anantharam A, Lewis A, Panaghie G, Gordon E, McCrossan ZA, Lerner DJ, Abbott GW. RNA interference reveals that endogenous Xenopus MinK-related peptides govern mammalian K+ channel function in oocyte expression studies. J Biol Chem 2003; 278(14): 11739-11745.

Anantharam A, Diversé-Pierluissi MA. Studies of endogenous G-protein-mediated pathways in neurons by whole-cell electrophysiology. Meth Enzymol 2001; 345: 51-59.

Anantharam A, Diversé-Pierluissi MA. Biochemical approaches to study interaction of calcium channels with RGS12 in primary neuronal cultures. Meth Enzymol 2001; 345: 60-70.